Oct1 Knockout Rat

TGRS5600

Animal Model
Slc22a1

Nomenclature
SD- Slc22a1 tm1sage

Zygosity Genotype
Homozygous

Colony Size
Limited Availability

$525.00

Availability: In stock

Please note: Commercial pricing applied and includes the price of the animal model only. Academic pricing available on quote request.

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Technical Information
This model contains an 11 bp bi-allelic deletion within exon 1 of the Slc22a1 solute carrier family 22 (organic cation transporter), member 1, encoding for the basolateral hepatocyte uptake transporter OCT1.

Technical Data

Diet Value
LabDiet #5R24 (RMH2500)
Age Weight Curve
Health Report
PDF Download

Research Applications

Research Application
• Drug transport
• Drug-drug interactions
• Drug metabolism
• Hepatotoxicity
Research Area
Uptake Transporters

Characteristics

Characteristics
• Oct1 (-/-) rats have increased exposure to specific substrates
Additional Information

Additional Information

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