For over 150 years, the common laboratory rat has been used as a model for human disease research as its size, cognitive abilities and physiology make it ideal for the study of a wide range of human disease. Horizon Discovery specializes in rapid generation of knockout (or knock down) rats, mice or rabbits.
What is a knockout rat?
Definition: A knockout rat or mouse is an animal model that has been engineered with a specific gene (or genes) disabled. They aid study of gene function and drug development in academic or pharmaceutical research into human diseases & genetic conditions.
Formerly Sage Labs, Horizon Discovery partners with the leading minds in ADMET, neurobiology, cardiovascular biology, and oncology to develop our SAGE® rodent research models for advanced disease research.
We have one of the widest ranges of genetically engineered rodent models and can also create custom knockout rat models to your requirements using CRISPR technology complimented with a range of services for drug discovery & basic research. This includes Neuroscience, ADMET, Cardiovascular and Oncology with more models being constantly developed.
|Parkinson's Disease||Alzheimer's Disease||Autism||Schizophrenia||Pain||Optogenetics|
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|Rbfox1||Cre lines coming soon:|