Dopamine Transporter DAT-Cre Rat

TGRA8330

Animal Model
Slc6a3-cre

Nomenclature
SD- Slc6a3-cretm1sage

Zygosity Genotype
Homozygous

Colony Size
Available

$525.00

Availability: In stock

Please note: Commercial pricing applied and includes the price of the animal model only. Academic pricing available on quote request.

Request a quote
OR
Technical Information
This model expresses cre-recombinase under the control of the endogenous dopamine transporter promoter enabling specific expression in dopaminergic neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of DAT. The DAT-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines.

Technical Data

Diet Value
LabDiet #5R24 (RMH2500)
Age Weight Curve
Health Report
PDF Download

Research Applications

Research Application
• Optogenetics
• DREDD
• Expression/knockout of floxed genes
Research Area
Optogenetics Rats

Characteristics

Characteristics
• Cre recombinase driven by endogenous DAT promoter
• No observed ectopic expression of cre
• Targeted insertion eliminates possible gene disruption that may occur in random insertion technologies such as BAC
Background Strain: Sprague-Dawley
Protocols & Documents
Reviews

Write Your Own Review

You're reviewing: Dopamine Transporter DAT-Cre Rat

How do you rate this product? *

 
1 1 star
2 2 star
3 3 star
4 4 star
5 5 star
Quality
Price
Value
Back to top