CamKIIa-Cre Rat

TGRL9170

Animal Model
CamKIIa-Cre

Nomenclature
LEH- CamKIIa-Cretm1sage

Zygosity Genotype
Homozygous

Colony Size
Limited Availability

$525.00

Availability: In stock

Please note: Commercial pricing applied and includes the price of the animal model only. Academic pricing available on quote request.

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Technical Information
This model expresses cre-recombinase under the control of the endogenous camkIIa promoter enabling specific expression in excititory neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of CamkIIa. The CamkIIa-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines.

Technical Data

Diet Value
LabDiet #5R24 (RMH2500)
Health Report
PDF Download

Research Applications

Research Application
• Optogenetics
• Expression/knockout of floxed genes
Research Area
Optogenetics Rats

Characteristics

Characteristics
• Cre recombinase driven by endogenous CamKIIa promoter
• No observed ectopic expression of cre
• Targeted insertion eliminates possible gene disruption that may occur in random insertion technologies such as BAC
Background Strain: Long Evans Hooded
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