GENESIS is a proprietary gene-engineering platform technology that enables virally-mediated isogeneic targeting of any endogenous gene in human cells. Using the technique precisely and stably altered genotypes exhbiting gain-of-function can be constructed in a range of cell-types (including normal cells).
GENESIS allows for the definitive and step-wise creation of even complex disease states and their partner normal genetic backgrounds at each stage as a perfect reference.
GENESIS has just received a prestigious Innovation in Cancer award from the Medical Futures Innovation Commission.
References
- Davies et al, patents pending 1998, 1999, 2002, 2003
- Bunz et al, NAR 33(18), 2005