Translational Genomics

Advances in DNA sequencing have allowed the genomes of nearly 200 species to be determined, unlocking the possibility to:

The challenge of unlocking this wealth of information, known as 'translational genomics' is the ability to engineer functional test systems (cell lines) that precisely recapitulate the genetic features under experimental investigation.

Horizon can deploy, on your behalf, the most precise and flexible genome-editing solution available so that any DNA sequence can be inserted, deleted or substituted at any target endogenous locus in any parental cell line. Spatial, inducible and conditional targeting strategies can be deployed meaning your biological question (rather than the limits of the technology platform) can always be put first.

More information on GENESIS™, our translational genomics platform.

Explore our custom cell line generation service  

Explore our inventory of genetically-defined cell lines  

Explore SAGE® Labs in vivo models  

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