Search

Genetically Defined Cell Lines

Horizon's expertise in understanding the key genetic drivers of cancer has been applied in conjunction with GENESIS™ to develop the award winning X-MAN™ (Gene-X, Mutant And Normal) human isogenic disease models. These have become colloquially known as 'patients-in-a-test-tube'.

X-MAN™ cell lines are patient relevant disease models and have become essential translational genomic tools that comprise some or all of the following key features:

Enlarge Image

It can take as long as 16 weeks or more with costs often running into the tens of thousands of dollars in reagents and personnel time to generate a custom cell line, which is then followed by a detailed validation process to demonstrate that a generated cell line harbors a single-copy of the genomic feature of interest (without any confounding off-target effects prevalent with nuclease-based targeting approaches). However, Horizon’s extensive and growing menu of almost 600 X-MAN™ cell lines and endogenous pathway and imaging reporter kits provide you with access to pre-made and highly validated cell lines and tools for a fraction of the cost of in-house development.

Learn more about our menu of X-MAN™ cell lines and X-MAN™ Reporter Kits  

×
×
×
×
×
×

Login Error


There was an error with your login - please try again.

Forgotten your password? Click here

OK ×

Recover your password

Please enter your email address and we'll send you a reset link

×

Thank you.


We've sent you an email to reset your password.

OK ×

Add Voucher


Sorry, Unable to add voucher

OK ×

Account Error


There was an error updating your details.

OK ×

Thank you.


Your changes have been saved.

OK ×

Thank you


Thank you for registering to the Horizon Discovery website. We hope you enjoy and benefit from our online resources, and please feel free to contact us if you have any queries or feedback through the website itself or at info@horizondiscovery.com.


Got a few seconds to tell us what you're interested in?



Tick all that apply:

Horizon’s Offerings

Application Area

Disease Area

 

Other Disease Area (Please specify)


OK
×

Thank you.


Items have been saved to your basket.

OK ×