Power up your discovery pipeline with Horizon CRISPR screening
Horizon offers comprehensive CRISPR screening services from screen design and cell line selection to sophisticated bioinformatics analysis of the screen results. Our best-in-class CRISPR KO (knockout), CRISPRi (interference) and CRISPRa (activation) screening platforms can significantly advance our customers’ drug development programs by offering the highest quality and highest confidence in their screening results.
Our expertise includes whole-genome and custom targeted drug resistance and sensitivity screens, synthetic lethality target discovery screens and complex phenotypic screens using a FACS-based readout. We have optimized 50+ cell lines for CRISPR screening and have completed over 300 screens to date.
We offer a choice of CRISPR screen types depending on the expression effect you require:
For more information use the links provided or contact our team.
Take a look at our poster about Dual CRISPRi & CRISPRa screening which helps to identify components that influence resistance and sensitivity to the standard of care BRAF inhibitor, vemurafenib:
View our webinar on the application possibilities of CRISPR screening: