piezo type mechanosensitive ion channel component 2
Alias
C18orf30 | C18orf58 | DA3 | DA5 | DAIPT | FAM38B | FAM38B2 | HsT748 | HsT771 | MWKS
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014].