NLR family CARD domain containing 4
Alias
AIFEC | CARD12 | CLAN | CLAN1 | CLANA | CLANB | CLANC | CLAND | CLR2.1 | FCAS4 | IPAF
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].