chibby family member 1, beta catenin antagonist
Alias
C22orf2 | CBY | HS508I15A | PGEA1 | PIGEA-14 | PIGEA14 | arb1
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].