Custom gene-edited cell lines with your chosen genotype
With nearly a decade of experience planning and executing nearly 3,000 gene editing experiments, access to a multiple genome editing technologies, and cell line development service options to suit a variety of experimental needs and budgets, Horizon is the global leader in cell line engineering.
Disruption of the gene X in the human melanoma A375 cell line (copy number = 3).
To create a heterozygous point mutation K700E (AAA -> GAA) in SF3B1 in chronic myelogenous leukemia (CML) K562 cells using rAAV.
Cell Line Characterization
Gene-editing Reagent Design
Cell Line Engineering
Cell Line Validation
Create translational in vitro disease relevant models
Customized gene editing of the CHO genome to optimize your bioproduction platform.
See our extensive panel of pre-characterized immune cell lines