With nearly a decade of experience planning and executing nearly 3,000 gene editing experiments, access to a multiple genome editing technologies, and cell line development service options to suit a variety of experimental needs and budgets, Horizon is the global leader in cell line engineering.
If you can't find the cell line you need for your experiment in our catalog; our team at Horizon Discovery can manage the cell line development for you.
|Proprietary Cell Line||Immortalized||iPSC||CHO|
Cell line background
|HAP1 cell lines||Any$||Provided by customer||Provided by customer or CHO Cells|
|Shipping||10-18 weeks*||10-32 weeks*||17-27 weeks*||Project dependent|
|Sanger sequencing||Sanger sequencing, additional genotyping and digital PCR*||Sanger sequencing and additional genotyping||Sanger sequencing and additional genotyping|
|Genetically modified cell line + matched control||Genetically modified cell line + isogenic control||Genetically modified iPSC line||Genetically modifed CHO cell|
|Knockout (Frameshift mutations and deletions), knockin, gene tagging||Knockout, knockin, deletions, translocations, reporters||Knockout, knockin, deletions, translocations, reporters||Knockout, knockin, deletions|
Gene editing technologies used
|CRISPR||CRISPR, rAAV, ZFNs or combination||CRISPR||CRISPR (R&D) or rAAV (manufacturing ready)|
Gene Tagging, Knockin, Deletions $3,400#
Knockout from $14,990
Knockin from $19,990
Pricing on request
Pricing on request
*Cell line and project dependent #Academic pricing $Cell line must tolerate single cell cloning and display adequate transfection efficiency
Gene editing technologies that Horizon offer
Horizon have licenses for both CRISPR and Zinc Finger Nucleases (ZFNs), which along with our proprietary genome editing technology, rAAV, means we can select the best tool for the job, and our customers do not have to worry about licensing.
Which genetic modifications can Horizon make?
To deliver your ideal engineered cell line, we are able to make almost any genetic alteration required, from simple knockouts or single point mutations to more complex genomic manipulations such as translocations.
|Reporter Cell Lines|