RNA-Based Screening in Drug Discovery – Introducing sgRNA Technologies

Category: Research Services



Presenter:  Dr. Jon Moore, CSO & VP Oncology, Horizon Discovery 

Horizon is a world-leader in genome-editing, and in this free webinar we discuss our approach to RNA-based screening using siRNA and CRISPR-Cas9 sgRNA technologies. Topics will include introduction to RNAi technologies, use of X-MAN® isogenic cell lines in RNAi screening approaches, comparison of siRNA and sgRNA screening approaches, possibilities and challenges of genome-wide CRISPR-Cas9 knockout (GeCKO) screening, and examples of synthetic lethal screenings using siRNA and CRISPR-Cas9 sgRNA technologies for target identification and patient stratification.

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