Our scientists are experts in the development and application of cell based assays for drug discovery projects and similar research. In addition to standard cell survival and proliferation assays, we can carry out co-culture assays to model the tumour microenvironment, analyse the effects of hypoxia through the use of spheroid assays or low oxygen incubators, grow cells in soft agar for medium throughput assessment of viability and proliferation, and examine senescence and autophagy induction.
Our ready-made and custom cell lines can be used in these assays and in oncology compound profiling, target validation and mechanism of action studies, patient stratification, and understanding disease biology.
We will work closely with you to design suitable studies to ensure that we address your scientific questions, and will aid with data interpretation where needed, thereby maximizing the success of your projects with us.
How does our service work?
|Cell Growth Assays||Standard Mechanistic assays||Specialist Assays||Assays for Target Validation|
siRNA and CRISPRi knockdown
CRISPR-Cas9 knockout and knock in
Invasion and migration assays
Tubulin polymerisation assay
Combination drug assays
Reporter cell lines
RNA, cell pellet and lysate preparation
Reactive oxygen species assays