Although CRISPR knockout screening has provided a powerful and precise solution to identify and validate novel drug targets, and to elucidate unknown drug mechanisms, there are some biological studies for which CRISPR knockout screens are not applicable. A CRISPR interference screen (CRISPRi) from Horizon Discovery can open up new opportunities for your research.
CRISPR Interference (CRISPRi) screening enables us to study reduced gene expression, rather than completely eliminating gene expression. These tools provide highly precise and sensitive screening solutions.
For more information on how CRISPR interference can help with your research, read Horizon’s blog post about CRISPRi and CRISPRa and their possibilities in functional genomic screening.