The acquisition of Dharmacon has expanded the Horizon Discovery portfolio to include a market-leading suite of research reagents for all aspects of gene modulation for functional analysis, including RNAi, CRISPR-Cas9, and CRISPR activation. Browse this page to browse to your product area of interest.
Optimized tools for high-confidence gene knockout.
The Edit-R™ CRISPR-Cas9 portfolio enables a wide range of applications for gene knockout, cell engineering, functional screening, and HDR.
Synthetic & lentiviral reagents for endogenous gene overexpression
Edit-R CRISPR activation (CRISPRa) reagents provide a straightforward, efficient set of tools to study a gene’s function by overexpression in its native context by 5 to 50,000+ fold!
Guaranteed silencing for high-quality, reproducible results
Dharmacon RNAi products encompass the most complete portfolio of innovative tools for transient, long-term, inducible and in vivo RNAi applications.
Unparalleled length, yield, and modification options to suit your needs
The innovative properties of Dharmacon 2´-ACE™ technology enable routine synthesis of RNA in high yield and of exceptional quality, higher purity, and greater yields compared to other synthetic methods.
Ectopic gene expression for gene analysis and protein science
Pre-cloned cDNAs and ORFs reduce the amount of time needed to clone or synthesize a gene of interest. Choose from individual clones, lentiviral ORFs, and genome-scale libraries for mammalian species and model organisms.
Specialized reagents for high-efficiency delivery of RNA, DNA, and protein
One of the key success factors in any gene modulation experiment (RNAi, overexpression, gene editing) is the introduction of RNA and/or DNA components into your cell line or in vivo system.