Oprm1 Knockout Rat

TGRA8540

Animal Model
Oprm1

Nomenclature
SD Oprm1 tm1sage

Zygosity Genotype
Heterozygous

Colony Size
Cryopreserved

$525.00

Availability: In stock

Please note: Commercial pricing applied and includes the price of the animal model only. Academic pricing available on quote request.

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Technical Information
This model possesses an 11 base pair deletion in exon 2 of the Oprm1 gene, leading to an early stop codon in exon 3. Oprm1 encodes the mu opioid receptor 1 (MOR), the major target of most clinically used opioids. This model is useful for applications investigating nociception, and is particularly useful for discrimination among opioid receptor subtypes.

Technical Data

Diet Value
LabDiet #5R24 (RMH2500)
Age Weight Curve
Health Report
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Research Applications

Research Application
• Nociception
• Pain
• Analgesia
• Addiction
Research Area
Pain

Characteristics

Characteristics
• 11 base pair deletion in exon 2
• Early stop codon in exon 3
Background Strain: Sprague-Dawley
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