Transgenic Mice

What is a Transgenic Animal?

Definition: Transgenic animals (commonly mice or rats) are those that have had their DNA altered through the addition of a foreign gene.

Transgenic mice

Transgenic mice have historically been the preferred species for in vivo research and animal models of human diseases such as cancer.

Transgenic Mouse Models

The use of CRISPR to make customized transgenic mouse models, has allowed Horizon to speed up the process of creating transgenic mice by eliminating the need for embryonic stem cells to generate genetic modifications in rodents.

By using CRISPR/Cas9 and ZFNs, both nuclease based genetic engineering technologies, we can generate transgenic mouse models to your exact specifications.

SAGEspeed Express: Your fastest, most efficient transgenic mouse models using CRISPR/Cas9

Mouse Model Generation

Advantages of Horizon's SAGEspeed services:

  • Optimized capabilities using the latest advancements in CRISPR/Cas9 technology to deliver genetically engineered mouse models even faster and more efficiently
  • Experience completing all project types using CRISPR/Cas9 including constitutive knockouts, point mutations, conditional knockouts, reporter tags, constitutive knockins, and humanized models.
  • Guaranteed germline transmission of your desired mutation

Let us build your ideal transgenic animal model:

Animal Model Quotation

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