Analyze the drug metabolism of your compounds with confidence using Horizon’s PXR, CAR, Double Knockout and wild-type (WT) SD Rat Hepatocytes.
Please view details of these Rat Hepatocytes that are available through our partnership with In Vitro ADMET Labroatories, Inc:
Gene Knockout | Horizon Rat Model # | IVAL Catalog # | Product Characterization Sheet # | Tested for Drug Metabolism Activity |
---|---|---|---|---|
Bcrp | TGRS4200 | 82118 | RS129 | ECOD, UGT, Sulfotransferase |
CAR | TGRS8190 | 82114 | RS132 | ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated |
Mdr1a | TGRS3570 | 82126 | RS131 | ECOD, UGT, Sulfotransferase |
Mdr1a/b | TGRS7070 | 82122 | RS130 | ECOD, UGT, Sulfotransferase |
PXR | TGRS4130 | 82169 | RS133 | ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated |
PXR/CAR | TGRS9100 | 82165 | RS134 | ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated |
WT SD Rat Hepatocytes | N/A | 82018 | RSM111 | ECOD, UGT, Sulfotransferase |