Primary Rat Hepatocytes

Analyze the drug metabolism of your compounds with confidence using Horizon’s PXR, CAR, Double Knockout and wild-type (WT) SD Rat Hepatocytes.

  • Pre-screened for plateability
  • Characterized for metabolic activity, CYP induction, and transporter efflux activity
  • Cryopreserved, maximized re-thaw viability (~90%), recovery, and plating efficiency
  • Available from single or multiple donors

Please view details of these Rat Hepatocytes that are available through our partnership with In Vitro ADMET Labroatories, Inc:

Gene KnockoutHorizon Rat Model #IVAL Catalog #Product Characterization Sheet #Tested for Drug Metabolism Activity
Bcrp TGRS4200 82118 RS129 ECOD, UGT, Sulfotransferase
CAR TGRS8190 82114 RS132 ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated
Mdr1a TGRS3570 82126 RS131 ECOD, UGT, Sulfotransferase
Mdr1a/b TGRS7070 82122 RS130 ECOD, UGT, Sulfotransferase
PXR TGRS4130 82169 RS133 ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated
PXR/CAR TGRS9100 82165 RS134 ECOD, UGT, Sulfotransferase, PCN and TCPOBOP Treated
WT SD Rat Hepatocytes N/A 82018 RSM111 ECOD, UGT, Sulfotransferase
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