What is a PDX Model?
A PDX model is typically implanted as dissociated cells into immunodeficient mouse models which may then be used for efficacy studies.
Bring clarity to your research with our catalog of well-characterized, deeply sequenced, patient derived xenograft models. Tumor heterogeneity is a challenge in cancer research and drug development. Examination of cancer cell lines does not offer a comprehensive view of a tumor or tumor microenvironment. This is where it can be helpful to examine a patient derived xenograft (PDX) model of tumors.
Explore our highly-characterised xenograft tumor models below, or read more about our PDX tumor models. In addition to PDX mice models we also provide a tumor growth service.
Browse our collection of patient-derived xenografts. Use the filters below to find the perfect PDX model for your application, and click on each line to view even more detail.
|WHIM#||PAM50 Subtype||Tumor Site||ER Status||HER2 Status||PR Status||ESR1 Genotype||Estradiol Response||Whole Genome Sequenced|
|Luminal A||Metastasis: Skin||Positive||Negative||Positive||AMP||Responsive||Yes|
|Luminal A||Metastasis: Node||Positive||Negative||Positive||Y537S||No|
|Luminal A||Metastasis: Node||Positive||Negative||Positive||WT||Yes|
|Luminal A||Metastasis: Skin||Positive||Negative||Positive||Y537S||Independent||Yes|