nuclear receptor subfamily 0 group B member 1
Alias
AHC | AHCH | AHX | DAX-1 | DAX1 | DSS | GTD | HHG | NROB1 | SRXY2
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008].