cyclic nucleotide gated channel alpha 1
Alias
CNCG | CNCG1 | CNG-1 | CNG1 | RCNC1 | RCNCa | RCNCalpha | RP49
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].