B-cell CLL/lymphoma 11B
Alias
ATL1 | ATL1-alpha | ATL1-beta | ATL1-delta | ATL1-gamma | CTIP-2 | CTIP2 | IMD49 | RIT1 | ZNF856B | hRIT1-alpha
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013].