Cntnap2 Knockout Rat

TGRS8820

Animal Model
Cntnap2

Nomenclature
SD- Cntnap2 tm1sage

Zygosity Genotype
Heterozygous

Colony Size
Cryopreserved

$525.00

Availability: In stock

Please note: Commercial pricing applied and includes the price of the animal model only. Academic pricing available on quote request.

Request a quote
OR
Technical Information
Generated in conjunction with Autism Speaks, this model possesses a bi-allelic deletion in the contactin associated protein-like 2 (Cntnap2) gene. A member of the neurexin family, Cntnap2 has been associated with the autism spectrum disorders.

Technical Data

Diet Value
LabDiet #5R24 (RMH2500)
Health Report
PDF Download

Research Applications

Research Application
• Autism Spectrum Disorders
• Language disorders
• Synaptic Plasticity
• Cell adhesion
Research Area
Autism

Characteristics

Characteristics
• This model was created in collaboration with Autism Speaks and is currently undergoing phenotypic characterization by Dr. Richard Paylor at Baylor College of Medicine
• Homozygous knockout rats exhibit complete loss of target protein as demonstrated by Western blot
• 5 base pair deletion in exon 6 of Cntnap2
• Spontaneous seizures >7 weeks of age
Background Strain: Sprague-Dawley
Figure 1
Cntnap2 Knockout Rat - Figure 1
Figure 1: Lack of Cntnap2 protein expression in homozygous Cntnap2 knockout rats.
Additional Information

Additional Information

Reviews

Write Your Own Review

You're reviewing: Cntnap2 Knockout Rat

How do you rate this product? *

 
1 1 star
2 2 star
3 3 star
4 4 star
5 5 star
Quality
Price
Value
Back to top