Generated in conjunction with Autism Speaks, this knockout rat model possesses a 13 bp deletion in the chromodomain helicase DNA binding protein encoded by the CHD8 gene and is a chromatin regulator enzyme that is essential during fetal development. CHD8 has been associated with autism spectrum disorders.
- Diet Value
LabDiet #5R24 (RMH2500)
- Research Application
- Research Area
• This model was created in collaboration with Autism Speaks
• 13 bp deletion in CHD8
• Background Strain: Sprague-Dawley