Quality Control

Horizon’s cell lines undergo extensive characterization pre- and post- gene-editing.

When appropriate the originating wild type cell line (e.g. SW48) can be single cell diluted to ensure a clonal population exists prior to gene editing. This clone goes through cell line validation (see below) and if successful is taken forward to gene editing.

The resulting clonal mutant cell line goes through the same rigorous cell line validation process

Cell Line Quality Control

Dependent on the project and its requirements combinations of the above genetic validation tests are employed.

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