Applications
Many leaders in the academic, biotechnology, diagnostics and pharmaceutical sectors, such as Agios, Actelion, AstraZeneca, DxS DiagnosticsGenentech, GSK, Novartis, OSI, Millenium, SuperGen and Cancer Research UK, are now using X-MAN cell lines in preference to historical cell-models because of their broad applicability in drug discovery and development research.
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Applications of X-MAN cell-lines:
• Identification of ‘patient-relevant’ drug targets
• Optimisation of drug candidates for clinical development
• Defining patient responsive genotypes early in discovery
• Design of shorter, less-expensive and more successful clinical trials
• Identifying rational combinations of drugs to address resistance mechanisms
• Re-positioning existing drugs from other therapeutic indications in cancer
• As ‘gold-standard’ research tools to validate genetic-based diagnostic kits
• Identification of novel companion Dx biomarkers and disease signatures
References
- GENESIS & X-MAN FAQ (Download)
Publications:
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