Current Disease Models

Applications

Many leaders in the academic, biotechnology, diagnostics and pharmaceutical sectors, such as Agios, Actelion, AstraZeneca, DxS DiagnosticsGenentech, GSK, Novartis, OSI, Millenium, SuperGen and Cancer Research UK, are now using X-MAN cell lines in preference to historical cell-models because of their broad applicability in drug discovery and development research.

X-MAN Applications in Drug Discovery

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Applications of X-MAN cell-lines:

•    Identification of ‘patient-relevant’ drug targets
•    Optimisation of drug candidates for clinical development
•    Defining patient responsive genotypes early in discovery
•    Design of shorter, less-expensive and more successful clinical trials
•    Identifying rational combinations of drugs to address resistance mechanisms
•    Re-positioning existing drugs from other therapeutic indications in cancer
•    As ‘gold-standard’ research tools to validate genetic-based diagnostic kits
• Identification of novel companion Dx biomarkers and disease signatures

References
Publications:

bookicon.gifKey Scientific Publications

bookicon.gifSelected User Publications