X-MAN Discovery 2
Discovery 2 lines encompass ‘gain-of-function’ models generated via the double knock-in of mutated cancer genes. These models accurately recapitulate known resistance mechanisms that lead to certain patient populations being unresponsive to marketed cancer drugs.
Example isogenic tumour vs. normal cell-lines (double KI or KO) available for immediate licensing (see full inventory in download below):
Click on the image to enlarge.
Latest X-MAN Inventory
Publications:
