Horizon is pleased to be able to offer its customers a range of custom cell-line engineering services using its proprietary GENESIS™ technology.

 

Example cell-line generation projects:

* KI of single genotype to model drugable target
* KI of double genotype to model drug resistance
* KI of oncogenes to DKI’s to induce tumorigenicity
* KI of SNP’s to create patient-predisposition models
* KI of GFP & LUC fusions to create in-vitro/in-vivo bridging tools
* KO of any gene to create functional genomics models
* KI of point mutation to inactivate gene or gene product
* KO of genes responsible for low-yield of expression proteins

The development of custom research tools will enable customers to become engaged in novel: target selectivity; target ID; drug resistance /combos /re-positioning and; bioproduction research and development.

Call us today on +44 (0) 1223 655580 or email us at xman@horizondiscovery.com to discuss how X-MAN products and services can target your specific research needs.

References

• Featured publications
• All publications

Downloads

• Horizon Technology Presentation
• Latest X-MAN Catalogue (view/ download)