Poster Exhibit

  • Poster presented at the Society for Laboratory Automation & Screening (SLAS 2012 – San Diego, CA) 

  • New Cellular Reporter Technologies Using X-MAN™ Cell Models

  • Paul Morrill, Chris Torrance, Christine Schofield, Holly Astley, Tom Henley, Claire Mahoney, Paul Gonzales, Bernardo Chavira, Mei Cong, Danette Daniels, Hélène Benink, Nancy Murphy, Jeff Kelly

  • View Article

  • Horizon Discovery Ltd, Cambridge, UK; and Laboratory of Molecular Genetics, Institute for Cancer Research and Treatment, Turin, Italy 

  • Isogenic K‐Ras mutant cancer cells: A novel platform for drug profiling

  • John Goodall, Jessica Hunt, Federica Di Nicolantonio, Margherita Gallicchio, Simona Lamba, Zhiqiang Chen, Alberto Bardelli, Chris Torrance and Kyla Grimshaw

  • View Article

  • Horizon Discovery Ltd & Celera Corp. USA 

  • Profiling the metabolic dependencies of PI3Kα mutant cancers

  • Rebecca Foster, Sue Rigby, Suzanne Grooby, Ruth Feltell, Cindy Christopherson, Monica Chang, John Sninsky, Shirley Kwok and Chris Torrance

  • View Article

  • Poster presented at AACR meeting 2011 

  • Investigation into the influence of the PI3Kα (H1047R) mutation on the bioenergetic dependency of a cell

  • Rebecca Foster, Sue Rigby, Ruth Feltell, Suzanne Mead, Cindy Christopherson, John Sninsky, Shirley Kwok and Chris Torrance.

  • View Article

  • BACR/RSM Oncology Section Meeting - Development of Cancer Medicines 

  • The use of PI3K isogenic cell lines in conditions that model the tumour microenvironment provides a relevant system in which to test PI3K inhibitor profiles

  • Sue Rigby, John E. Goodall, Rebecca E. Foster, Suzanne Mead, Zhiqiang Chen, Rob Howes, Chris Torrance, Kyla M. Grimshaw

  • View Article

  • BACR/RSM Oncology Section Meeting - Development of Cancer Medicines 

  • Development of a multicellular tumour spheroid model to study the hypoxic tumour microenvironment

  • Rebecca E. Foster, Suzanne Mead and Kyla M. Grimshaw

  • View Article

  • Poster presented at EORTC meeting 2010 

  • External quality control for companion molecular diagnostics using genetically-defined human isogenic cell lines

  • Sharon J Glaysher, Penny Johnson, Louise Bolton, Francis G Gabriel, Ian A Cree

  • View Article

  • Poster presented at EORTC 2010 

  • GDC-0941 and ABT-737 cooperate to sensitize isolated mitochondria from PI3K mutant cells

  • Nelly Buron, Mathieu Porceddu, Darin Disley, Chris Torrance and Annie Borgne-Sanchez

  • View Article

  • Poster presented at AACR 2010 

  • Endogenous expression of oncogenic PI3K mutation leads to accumulation of anti-apoptotic proteins at mitochondria

  • Nelly Buron, Mathieu Porceddu, Darrin Disley, Chris Torrance, Annie Borgne-Sanchez, Mitologics S A S

  • View Article

  • Poster presented at AACR, 2010 

  • Mutant PIK3CA increases the expression of individual tubulin isoforms and promotes resistance to anti-mitotic chemotherapy drugs

  • Jeffrey J. Wallin, Jane Guan, Yang Xiao, Tom O’Brien, Marcia Belvin and Lori S. Friedman. Genentech Inc.

  • View Article

  • Poster presented at AACR, 2010 

  • The use of X-MAN isogenic cell lines to define PI3-kinase inhibitor activity profiles

  • John E. Goodall, Rebecca E. Foster, Suzanne Mead, Sue Rigby, Zhiqiang Chen, Chris Torrance and Kyla M. Grimshaw

  • View Article

  • Poster presented at AACR, 2010 

  • Endogenous expression of an oncogenic PI3K mutation leads to activated PI3K pathway signalling and an invasive phenotype

  • Jane Guan, Peter M. Haverty, Zora Modrusan, Sabrina Arena, Evelyn Yao, Klaus P Hoeflich, Alberto Bardelli, Christopher Torrance, Marcia Belvin, Lori S Friedman, Jeffrey J Wallin, Genentech Inc.

  • View Article

  • Poster presented at AACR, 2009 

  • Investigation into the mechanism of action of the ruthenium(II) organometallic complex, ONCO 4417

  • Rebecca E. Foster, Daniel A. Cole, Suzanne Mead, Peter J. Sadler and Kyla M. Grimshaw, Hypoxium Ltd.

  • View Article