Comparison of Gene-Editing Techniques

rAAV GENESIS™, by using exclusively the homologous recombination DNA repair pathway, is the only approach that enables any genomic alteration (e.g. point mutations, amplifications, translocations) to be made with the highest level of precision and in a spatial, inducible or conditional context. If you have complex biological questions to address that require flexible, precise and error free genome-editing then rAAV GENESIS™ is the best solution for your research.

 

Model
Zinc-Finger nucleases Med High Low/Med Med NHEJ Low/Med
Meganucleases Med High Low/Med Med NHEJ Low/Med
TALE-nucleases Med High Low/Med Med NHEJ Low/Med
rAAV GENESIS™ High Med High High HR

Low/Med

To learn more about the differences between rAAV and nuclease-based gene-editing, download our technology comparison document 'Genome Editing with rAAV: A More Precise and Flexible Alternative to Nucleases'  

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