Gene Editing
Historical Perspectives Precision Gene Editing with rAAV Vectors Comparison of Gene Editing TechniquesPublications
rAAV GENESIS™, by using exclusively the homologous recombination DNA repair pathway, is the only approach that enables any genomic alteration (e.g. point mutations, amplifications, translocations) to be made with the highest level of precision and in a spatial, inducible or conditional context. If you have complex biological questions to address that require flexible, precise and error free genome-editing then rAAV GENESIS™ is the best solution for your research.
| Model | ||||||
|---|---|---|---|---|---|---|
| Zinc-Finger nucleases | Med | High | Low/Med | Med | NHEJ | Low/Med |
| Meganucleases | Med | High | Low/Med | Med | NHEJ | Low/Med |
| TALE-nucleases | Med | High | Low/Med | Med | NHEJ | Low/Med |
| rAAV GENESIS™ | High | Med | High | High | HR |
Low/Med |
To learn more about the differences between rAAV and nuclease-based gene-editing, download our technology comparison document 'Genome Editing with rAAV: A More Precise and Flexible Alternative to Nucleases'
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